PERSONAL CARE AND COSMETICS
Vitamin E TPGS is finding applications in personal care and cosmetic products. In addition to providing water-soluble vitamin E, it is a powerful tool in formulating other actives. Specifically, TPGS Serves as an ethanol free, hypoallergenic, non-irritating emulsifier/excipient for personal care and cosmetic products. It may be used to solubilize poorly soluble actives. TPGS The International Nomenclature of Cosmetic Ingredients (INCI) lists TPGS as Tocophersolan.
Applications of vitamin E TPGS in personal care and cosmetics include:
- Eye drops, nasal sprays, syrups and others primarily in formulating active compounds.
- Creams, lotions and other products for topical application of vitamin E and other formulated actives.
For a summary of the TPGS vitamin E activity and other nutrient data which are useful in meeting the labeling requirements of the Food and Drug Administration (FDA) and other regulatory agencies in the United States and internationally please see the Nutrient Data Sheet.
Selected references
- Ahuja M, Dhake AS, Sharma SK, Majumdar DK. Topical ocular delivery of NSAIDs. AAPS J. 2008 Jun;10(2):229-41.
- Aydemir O, Celebi S, Yilmaz T, Yekeler H, Kükner AS. Protective effects of vitamin E forms (alpha-tocopherol, gamma-tocopherol and d-alpha-tocopherol polyethylene glycol 1000 succinate) on retinal edema during ischemia-reperfusion injury in the guinea pig retina. Int Ophthalmol. 2004 Oct-Dec;25(5-6):283-9.
- Le Bourlais CA, Chevanne F, Turlin B, Acar L, Zia H, Sado PA, Needham TE, Leverge R. Effect of cyclosporine A formulations on bovine corneal absorption: ex-vivo study. J Microencapsul. 1997 Jul-Aug;14(4):457-67.
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